What NOT to Mix with Retinoids: A Guide to Glowing Skin

Retinoids are the ultimate multitaskers in skincare, tackling everything from fine lines and wrinkles to acne and uneven skin tone. But even these powerhouse ingredients need the right partners to work their magic effectively. Pairing retinoids with the wrong ingredients can lead to irritation, redness, or diminished results.

Let’s break down the best and worst pairings for retinoids, ensuring your skincare routine keeps your complexion healthy and radiant. 

What Works Well with Retinoids

1. Hyaluronic Acid
Retinoids can sometimes leave your skin feeling dry or flaky. Enter hyaluronic acid—a hydration superstar. This ingredient locks in moisture, keeping your skin plump and balanced while minimising potential dryness from retinoids.

2. Niacinamide
Niacinamide is a soothing, anti-inflammatory ingredient that pairs perfectly with retinoids. It strengthens the skin barrier, reduces redness, and helps your skin tolerate retinoids better.

3. Ceramides
Retinoids can weaken the skin barrier, but ceramides are here to save the day. These essential lipids restore your barrier function, reducing sensitivity and keeping irritation at bay.
 

What to Avoid with Retinoids

1. Vitamin C
Vitamin C and retinoids are both anti-aging powerhouses, but they don’t mix well. Vitamin C is most effective in the morning to combat free radicals from sun exposure, while retinoids work best at night. Combining them can lead to skin irritation and reduce their effectiveness.

2. Azelaic Acid
Both azelaic acid and retinoids target acne and pigmentation, but layering them increases the risk of excessive dryness and irritation. Alternate between these ingredients on different nights for best results.

3. Benzoyl Peroxide
Benzoyl peroxide is a potent acne treatment, but it can deactivate retinoids. To avoid compromising either product, use benzoyl peroxide in the morning and retinoids at night.

4. Essential Oils
While essential oils are often praised for their soothing properties, they can be too harsh when combined with retinoids, leading to unwanted irritation. Skip the oils when using retinoids in your routine.
 

Tips for a Skin-Loving Retinoid Routine

  • Start Slow: Introduce retinoids gradually, applying them 2–3 times a week to allow your skin to adapt.
  • Layer Wisely: Apply hydrating or soothing ingredients like hyaluronic acid or ceramides after retinoids to counteract dryness.
  • Use Sunscreen: Retinoids increase photosensitivity, so wear a broad-spectrum SPF daily to protect your skin.
  • Alternate Active Ingredients: For ingredients like azelaic acid or benzoyl peroxide, use them on different days or times of the day to avoid irritation.

 The Bottom Line

Retinoids can transform your skin, but only when used correctly. By pairing them with complementary ingredients like hyaluronic acid, niacinamide, and ceramides, and steering clear of clashing actives like vitamin C and benzoyl peroxide, you can maximise their benefits while minimising side effects.

Create a routine that suits your skin’s needs, and enjoy the smooth, radiant complexion that retinoids can deliver!Retinoids

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